Figure 2.
Scn8a+/− mice exhibit greater freezing to training context and tone than WT mice. (A) As training progressed, both Scn8a+/− mice (N = 15) and WT mice (N = 13) exhibited increases in freezing to training context with Scn8a+/− mice freezing significantly more than WT mice. (B) Scn8a+/− mice exhibited greater freezing to context upon 5 minute exposure to training context than WT mice. (C) Scn8a+/− mice exhibited greater generalization of fear to the reconfigured context and greater freezing to tone than WT mice. All data are presented as mean ± S.E.M.
