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Scn8a+/− mice exhibit increased immobility in the forced swim test. (A) Latency to first bout of immobility was significantly shorter in Scn8a+/− mice (N = 12) than WT mice (N = 9). (B) Scn8a+/− mice spent significantly more total time immobile than WT mice. All data are presented as mean ± S.E.M. (*) p < 0.05; unpaired t-test.
