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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Mod Pathol. 2010 Mar 12;23(6):844–855. doi: 10.1038/modpathol.2010.60

Fig. 5.

Fig. 5

Immunoreactivity of p53, Ki-67, Rsf-1, cyclin E, FASN and mucin-4 in a STIC located in the fimbria (patient 11). Upper panel shows the STIC at low magnification. The epithelial cells at the right margin of the STIC show intense p53 expression but lack Ki-67 immunoreactivity (boxes). In the Middle and Lower panels the increased Rsf-1 and cyclin E immunoreactivity is confined to the same region (intense p53 expression but no Ki-67 immunoreactivity). In contrast, FASN is overexpressed only in the region where there is strong p53 expression and an elevated Ki-67 proliferation index. Mucin-4 immunoreactivity (lower panel) is largely absent in the STIC but positive in the normal tubal epithelium.