Table 2.
Influence of zinc supplementation on the outcome of high stool volume in different subgroups based on the isolated organisms.a
| Subgroup | N | Zn verses Pl | Zn + Cu verses Pl | Any zincb verses Pl | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| ORc | 95% CI | P | OR | 95% CI | P | OR | 95% CI | P | ||
| Overall | 798 | 0.88 | 0.62–1.26 | .496 | 0.88 | 0.62–1.25 | .472 | 0.88 | 0.65–1.20 | .418 |
| E. coli infection | 449 | 1.17 | 0.72–1.89 | .519 | 1.41 | 0.87–2.26 | .159 | 1.29 | 0.85–1.95 | .236 |
| E. coli single infection | 273 | 0.97 | 0.52–1.81 | .922 | 1.20 | 0.65–2.22 | .560 | 1.08 | 0.63–1.86 | .776 |
| Klebsiella infection | 275 | 0.67 | 0.36–1.24 | .204 | 0.55 | 0.30–1.03 | .062 | 0.61 | 0.36–1.04 | .071 |
| Klebsiella single infection | 170 | 0.70 | 0.31–1.58 | .395 | 0.48 | 0.21–1.08 | .077 | 0.58 | 0.29–1.18 | .131 |
| Rotavirus infection | 169 | 1.44 | 0.62–3.39 | .398 | 2.31 | 0.99–5.39 | .052 | 1.85 | 0.89–3.84 | .097 |
| E. coli + rotavirus mixed infection | 100 | 1.19 | 0.35–4.00 | .781 | 2.44 | 0.72–8.27 | .151 | 1.74 | 0.59–5.09 | .313 |
| Klebsiella + rotavirus mixed infection | 53 | 0.92 | 0.14–6.08 | .930 | 2.09 | 0.37–11.9 | .408 | 1.51 | 0.32–7.07 | .601 |
aAll the results are from multivariate logistic regression analyses which adjusted for effects of age, gender, presence of stunting (weight-for-age z-score <−2), presence of wasting (length-for-age z-score <−2), wealth index score, hand washing score, baseline plasma zinc level, baseline plasma copper level, and baseline hemoglobin level.
bChildren receiving zinc alone or zinc and copper compared to those receiving placebo.
cOR: odds ratio; CI: confidence interval; N: number of subjects with complete covariate information; Zn: zinc, Zn + Cu: zinc and copper; Pl: placebo.