Figure 2.

Association of HJURP mRNA levels with clinic and pathological factors in patients with breast cancer. There was no significant association between HJUPR mRNA levels and (a) ERBB2 (erythroblastic leukemia viral oncogene homolog 2) status, or (b) lymph node status, or (c) pathological stage or (d) tumor size. There were significant higher mRNA levels of HJURP in (e) estrogen receptor (ER) negative patients, (f) progesterone receptor (PR) negative patients; higher mRNA levels of HJURP were significantly associated with (g) high SBR grade, (h) younger age, and (i) Ki67 proliferation indices. HJURP expression is measured as log₂ (probe intensities) by Affymetrix microarray. The two-tailed P-values were obtained by Mann-Whitney U test for ERBB2, lymph node, ER and PR status, Kruskal-Wallis H test for pathological stage and SBR grade, and Spearman correlation for size, age, and Ki67 proliferation indices.