Table 4.
Results of multivariate analysis of independent prognostic factors in patients with breast cancer using Cox regression
| Disease-Free survival | Overall survival | |||
|---|---|---|---|---|
| Factor | Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value |
| HJURP expression+ | 2.05 (1.18 to 3.58) | 0.011 | 1.83 (1.11 to 3.01) | 0.018 |
| Lymph node (positive) | 3.76 (1.16 to 12.25) | 0.028 | 2.72 (1.08 to 6.88) | 0.035 |
| High Stage | 2.23 (1.08 to 4.59) | 0.030 | 1.85 (0.94 to 3.63) | 0.075 |
| Tumor size | 1.32 (0.97 to 1.79) | 0.079 | 1.34 (1.02 to 1.77) | 0.038 |
| Age (year) | 1.01 (0.99 to 1.05) | 0.33 | 1.03 (1.004 to 1.053) | 0.022 |
| High SBR Grade | 0.76 (0.33 to 1.75) | 0.52 | 1.00 (0.50 to 2.00) | 0.99 |
| ER (positive) | 0.63 (0.21 to 1.94) | 0.42 | 0.86 (0.33 to 2.25) | 0.75 |
| PR (positive) | 0.90 (0.33 to 2.50) | 0.84 | 0.95 (0.40 to 2.26) | 0.91 |
+ HJURP expression is measured as log2 (probe intensities) by Affymetrix microarray