Table 5.
Both HJURP mRNA levels and molecular subtypes are independent prognostic factors in patients with breast cancer using Cox regression#
| Disease-Free survival | Overall survival | |||
|---|---|---|---|---|
| Factor | Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value |
| HJURP | 6.19E-07 | 0.00011 | ||
| High vs Low | 3.26 (2.01 to 5.28) | 1.72E-06 | 3.23 (1.85 to 5.62) | 3.65E-05 |
| Moderate vs Low | 3.34 (2.11 to 5.27) | 2.3E-07 | 2.89 (1.68 to 4.95) | 0.00012 |
| Molecular Subtypes | 0.0069 | 0.00012 | ||
#The results are obtained from the combination of three data sets (reference 14, Dataset 1 and 3) where the information of the molecular subtypes (Normal like, Luminal, Erbb2 and Basal) was available.