Fig. 2.
Lung tissue NOx and tetrahydrobiopterin levels after LPS exposure. Tissue NOx levels are significantly decreased 2 h after LPS exposure. However, NOx levels were significantly increased 4- and 12-h after LPS exposure (A). Lung BH4 levels were measured by HPLC. There was no change in BH4 levels 2 h after LPS exposure, but BH4 levels were significantly increased 4- and 12-h post LPS treatment (B). Values are mean±SE, N=5 for each group. *P<0.05 compared to no LPS, †P<0.05 compared to previous time point.