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. Author manuscript; available in PMC: 2011 Jan 15.
Published in final edited form as: J Immunol. 2009 Dec 9;184(2):895–901. doi: 10.4049/jimmunol.0901230

FIGURE 2.

FIGURE 2

Trafficking of M. tuberculosis from the lungs to the MDLN and spleen is delayed in CCR7−/− mice compared with controls. CCR7+/+ and CCR7−/− mice were sacrificed at the indicated time points after aerosol infection with a low dose of M. tuberculosis and colony-forming units were determined in homogenates of lungs, mediastinal lymph node, and spleen. Data are represented as mean ± SD of four mice per group and per time point. * P< 0.05, ** P<0.005, *** P<0.001 by unpaired Student’s t test.