Fig. 4.
Insulin secretion from INS-1 cells in response to glucose (5 and 25 mM) after incubated for 5 days in control, IHG and SHG. Data are means ± SD of three separate experiments. C, control; IHG, intermittent high glucose; SHG, sustained high glucose. aP < 0.05 vs. control of 25 mM glucose, bP < 0.05 vs. IHG of 25 mM glucose.