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. 2010 Jun;62(2):199–236. doi: 10.1124/pr.109.002469

Fig. 10.

Fig. 10.

Analysis using immunohistochemistry of insulin expression by islets from N4 CD-1 mice. a–f, pancreata from 2-month-old, untreated nontransgenic (Con) (a) and transgenic (Tg) (d) mice, nontranstgenic (b) and transgenic (e) mice treated with streptozotocin (STZ) for 2 weeks, whereas other nontransgenic (c) and transgenic (f) mice were treated for 4 months. Magnification, 400×. g–j, analysis of 6-month-old, untreated nontransgenic (g) and transgenic (h) mice and nontransgenic (i) and transgenic (j) mice treated for 4 months with STZ. Magnification, 40×. [Reproduced from George M, Ayuso E, Casellas A, Costa C, Devedjian JC, and Bosch F (2002) β Cell expression of IGF-I leads to recovery from type 1 diabetes. J Clin Invest 109:1153–1163. Copyright © 2002 American Society for Clinical Investigation. Used with permission.]