Fig. 3.

Plasma TNF-α (top) and IL-6 levels (bottom) (in pg/ml) in sham-operated A₁WT mice (A₁WT sham, n = 4) and A₁KO mice (A₁KO sham, n = 4), A₁WT mice (A₁WT hepatic IR, n = 6) or A₁KO mice (A₁KO hepatic IR, n = 5–8) subjected to 60 min of hepatic ischemia and 24 h of reperfusion, and A₁WT mice pretreated with 0.4 mg/kg DPCPX (A₁WT hepatic IR+DPCPX, n = 5–8) or 0.1 mg/kg CCPA (A₁WT hepatic IR+CCPA, n = 5) and subjected to 60 of min hepatic ischemia and 24 h of reperfusion. Data are presented as means ± S.E.M. *, P < 0.05 versus A₁WT or A₁KO sham group. #, P < 0.01 versus A₁WT hepatic IR group.