TABLE 1.
Genotype frequency and mRNA and protein expression by CYP2C8 genotypes for human livers from 60 white individuals
Mean ± S.D. reported where appropriate.
| Genotype | CYP2C8*1/*1 | CYP2C8*1/*1 | CYP2C8*1/*1 | CYP2C8*3/*1 |
|---|---|---|---|---|
| Genotype frequency | ||||
| Number of livers (of 57 total genotyped) | 38 | 12 | 5 | 2 |
| Frequency | 0.67 | 0.21 | 0.09 | 0.04 |
| mRNA expression | ||||
| Number of livers | 33 | 12 | 5 | 2 |
| Relative value | 18181 ± 9912 | 22482 ± 13294 | 18587 ± 10884 | 10279 |
| Protein expression | ||||
| Number of livers | 33 | 11 | 5 | 2 |
| Amount (pmol/mg protein) | 30.8 ± 17.5 | 37.3 ± 15.2 | 15.8 ± 9.7 | 21.3 |