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. 2010 May 25;123(12):2094–2102. doi: 10.1242/jcs.057505

Fig. 7.

Fig. 7.

Androgen and Src signaling promote γ-tubulin accumulation at the centrosome. (A) Androgen signaling promotes γ-tubulin accumulation at the centrosome. HFFs treated with either control or AR siRNA were serum starved and replated onto fibronectin as indicated. The area of γ-tubulin staining at the centrosome was quantified from regrowth assays. (B) The Src kinase inhibitor, SU6656, inhibits γ-tubulin accumulation at the centrosome. The area of γ-tubulin staining at the centrosome was quantified from regrowth assays. (A,B) The mean values ± s.d. calculated from 75 cells per condition in each of three independent experiments. *A statistically significant difference from the CCM1 control (P<0.05). (C) Western blot analysis of γ-tubulin protein levels in cells replated onto fibronectin for 2 hours in either CCM1 or SF DMEM.