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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2010 Apr 8;30(6):1118–1126. doi: 10.1161/ATVBAHA.109.200873

Figure 2. The loss of Dicer in VSM causes structural abnormalities.

Figure 2

Cross-sections of Dfl/wt (A,B) and SMC-Dicer KO (C,D) dorsal aorta from E15.5 embryos. The white boxed region in panels A and C (12,000x) are depicted in panels B and D under higher magnification (60,000x). Arrows denote elastic lamellae and arrowheads point to dense plaques and myofilament arrays seen most prevalently in SMC of wildtype aorta. lu, lumen.