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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Epigenomics. 2009 Dec 1;1(2):331–345. doi: 10.2217/epi.09.31

Table 1.

Overview of next-generation DNA sequencing technologies.

Platform PCR mechanism Synthesis method Read-length (bp) Parallel reads
454 Emulsion PCR Pyrosequencing 200–500 1 million
Solexa Bridge PCR Reversible terminators up to 75 150 million
SOLiD Emulsion PCR Ligation up to 50 400 million