Table 4.
Percent change for hormone concentrations per unit increase in the independent variables (p values) from multivariate linear regression models with adjustments for maternal age, parity, weight, height, and smoking at enrollment in 338 uncomplicated pregnancies from the Northern Sweden Maternity Cohort, 1975–2001*
Independent variable | Dependent variable (hormones) | |||
---|---|---|---|---|
IGF-I | IGF-II | AFP | hCG | |
Maternal age (years) | −0.014 (0.01) | −0.017 (<0.0001) | ||
Multiparous vs. primiparous | 0.108 (0.04) | −0.150 (0.05) | ||
Maternal weight (kg) | −0.010 (0.01) | |||
Maternal smoking (yes vs. no) | −0.166 (0.03) |
for IGF-I, IGF-II, and AFP, models were adjusted for a linear term of gestational day; for hCG, models were adjusted for a cubic term of gestational day.