Film autoradiographs from coronal sections depict expression of the GABAA receptor γ2S subunit in adult wild type (A,C,E) and uPAR-/- (B, D, F) mice. The region of interest analyzed in frontal (A) and parietal (C) cortex, striatum (C), and the different subfields of the hippocampus (E) are indicated. Quantitative analysis (E) reveals a significant increase in γ2S message in parietal cortex, and a decrease in the CA3 subfield of the hippocampus. Asterisks, significantly different than wild type (p< 0.05). Fr, frontal cortex; Par, parietal cortex; Occ, occipital cortex; DG, dentate gyrus; Str, striatum.