Table 1.
WFA resulted in more focused tagSNPs selection
| Genesize quintile | Number of genes | SNPSpD a | WFAa | Agreementb |
|---|---|---|---|---|
| African-American | ||||
| 1 | 45 | 486 (10.8) | 145 (3.2) | 0.80 |
| 2 | 41 | 931 (22.7) | 272 (6.6) | 0.52 |
| 3 | 22 | 763 (34.7) | 210 (9.5) | 0.53 |
| 4 | 12 | 475 (39.6) | 152 (12.7) | 0.51 |
| 5 | 9 | 404 (44.9) | 185 (20.6) | 0.50 |
| Total | 129 | 3,059 (23.7) | 964 (7.5) | 0.62 |
| Caucasian | ||||
| 1 | 58 | 466 (8.0) | 161 (2.8) | 0.72 |
| 2 | 43 | 703 (16.3) | 284 (6.6) | 0.59 |
| 3 | 14 | 352 (25.1) | 161 (11.5) | 0.64 |
| 4 | 11 | 348 (31.6) | 141 (12.8) | 0.52 |
| 5 | 3 | 100 (33.3) | 56 (17.7) | 0.64 |
| Total | 129 | 1,969 (15.3) | 803 (6.2) | 0.62 |
a
Total number of SNPs selected as tagSNPs by SNPSpD and WFA for all genes in quintile (average SNPs per gene in quin-tile).
b
The proportion of SNPs selected by WFA also selected by SNPSpD.