Table 3.
Performance of the 4 analytical methods in related samples with various polygenic variances
| Polygenic variances |
|||
|---|---|---|---|
| 0.2 | 0.3 | 0.4 | |
| Power, % | |||
| SAT | 85.6 | 85.2 | 83.6 |
| ELRTP | 84.9 | 85.1 | 83.8 |
| ELRTR | 84.7 | 84.5 | 84.6 |
| GC | 82.7 | 81.9 | 81.8 |
| Type I error rates, % | |||
| SAT | 4.8 | 5.5 | 7.0 |
| ELRTP | 3.0 | 3.4 | 3.5 |
| ELRTR | 3.0 | 3.0 | 3.0 |
| GC | 4.1 | 5.0 | 5.5 |
SAT = Simple association test without correcting for cryptic relatedness; ELRTP = extended likelihood ratio test using PLINK inferred kinship coefficients; ELRTR = extended likelihood ratio test using real kinship coefficients; GC = genomic control.