Table 2.
Analytes differentiating AD from cognitively normal according to random forest analysis
| AD versus cognitively normal |
Z score |
|---|---|
| MAP model | |
| PDGF | 27.585 |
| IL-1α | 26.656 |
| IL-23 | 20.686 |
| C3 | 18.343 |
| Fabp | 17.888 |
| NrCAM | 15.937 |
| VEGF | 13.894 |
| TRAIL-R3 | 12.064 |
| IL-17 | 11.209 |
| Eotaxin-3 | 11.037 |
| IL-7 | 10.48 |
| A2M | 9.603 |
| Prolactin | 9.549 |
| Ferritin | 8.463 |
| ThBG | 8.371 |
| I-309 | 7.743 |
| HCC-4 | 3.502 |
| Traditional AD model | |
| Aβ42 | 68.401 |
| Tau | 21.826 |
| Male gender | 10.052 |
| Combined model | |
| Aβ42 | 47.935 |
| Tau | 26.232 |
| PDGF | 22.506 |
| IL-1α | 19.806 |
| NrCAM | 17.474 |
| C3 | 16.702 |
| IL-23 | 14.472 |
| VEGF | 13.362 |
| Fabp | 11.583 |
| Prolactin | 11.533 |
| TRAIL-R3 | 9.779 |
| A2M | 9.425 |
| I-309 | 7.981 |
| Calcitonin | 5.824 |
| Adiponectin | 4.64 |