Table 1.
Compd | Optical Activity | Optical rotation [α] (C = 0.1 in EtOH) | HPLC Purity (−) : (+) |
---|---|---|---|
14 | (S, +, S) | −9.7 ± 0.5° | 0.49 : 99.51 |
10 | (S, +/−, S) | −29.0 ± 1.0° | 49.43 : 50.57 |
13 | (S, −, S) | −49.0 ± 1.0° | 99.13 : 0.87 |
11 | (R, −, R) | +17.7 ± 0.5° | 99.50 : 0.5 |
9 | (R, +/−, R) | +35.0 ± 0.5° | 49.8 : 50.2 |
12 | (R, +, R) | +53.0 ± 1.5° | 0.39 : 99.61 |
4 | (RS, +/−, RS) | +1.0 ± 0.5° | 48.16 : 51.84 |
(R) | +34.2 ± 0.1° a* | 99 : 1 | |
(S) | −32.8 ± 0.1° b* | 99 : 1 |
Optical activity [α]22/D + 35.0°, C = 1 in Ethanol, commercially available from Sigma-Aldrich.
Optical activity [α]22/D − 35.0°, C = 1 in Ethanol, commercially available from Sigma-Aldrich.