Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Plasma stability, Microsomal stability, and Cell Membrane Permeability of diastereoisomers 11–14.
| Compound | Plasma stability (T = 1 h) | Microsomal Stability (T = 40 min) | Cell Permeability (LogPe) |
|---|---|---|---|
| 11 | 41% | 89.6 ± 7.0 % | −6.70 ± 0.30 |
| 12 | 28% | 83.4 ± 8.1 % | −7.69 ± 0.14 |
| 13 | 42% | 86.3 ± 7.0 % | −7.78 ± 0.06 |
| 14 | 41% | 91.6 ± 1.6 % | −7.85 ± 0.13 |
