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. Author manuscript; available in PMC: 2010 Jun 4.
Published in final edited form as: J Exp Zool B Mol Dev Evol. 2009 Jun 15;312B(4):292–308. doi: 10.1002/jez.b.21266

Fig. 7.

Fig. 7

The apoptotic rate and mitotic index in the R2 bud and molar epithelium at embryonic day 13.5. Two segments of dental epithelium (represented in the aerial view in 3D reconstructions at the top) of wild-type (WT) and Spry2−/− embryos were evaluated; colors as in legend. R2 and M refer to the segment of the rudimentary diastemal bud and molar epithelium, respectively. Representative dental epithelia are shown in the frontal sections below the reconstructions, and have been adjusted to the graphs. Compared with the molar region, note the higher level of apoptosis in the R2 in controls, and its dramatic decrease in mutants. In contrast, the mitotic index was significantly lower in the R2 than in the molar region in controls and significantly increased in mutants.