Skip to main content
. Author manuscript; available in PMC: 2011 Mar 25.
Published in final edited form as: J Med Chem. 2010 Mar 25;53(6):2562–2576. doi: 10.1021/jm9018542

Figure 3.

Figure 3

Changes in intracellular calcium in 1321N1 human astrocytoma cells stably expressing the hP2Y1 receptor. Fluorescence in response to a known hP2Y1 receptor agonist 2-MeSADP (EC50 10.3±0.4 nM), compound 3 (EC50 722±55 nM), or the phosphonate analogues (compounds 4 – 11, all inactive at 10 µM) was quantified using a FLIPR-Tetra.