Table 2.
HbA1c Concentrations by Hormonal Quartile Among 200 Non-HT Using Postmenopausal Women in the Women's Health Study
| Serum markers | Model 1a | Model 2b |
|---|---|---|
| SHBG, nmol/Lc | ||
| Quartile 1 | 5.34 | 5.31 |
| Quartile 2 | 5.14 | 5.11 |
| Quartile 3 | 5.08 | 5.111 |
| Quartile 4 | 5.09 | 5.14 |
| P for trend | 0.003 | 0.09 |
| Testosterone, ng/dLc | ||
| Quartile 1 | 5.10 | 5.11 |
| Quartile 2 | 5.19 | 5.21 |
| Quartile 3 | 5.13 | 5.12 |
| Quartile 4 | 5.24 | 5.22 |
| P for trend | 0.12 | 0.37 |
| Estradiol, pg/mLc | ||
| Quartile 1 | 5.07 | 5.12 |
| Quartile 2 | 5.17 | 5.19 |
| Quartile 3 | 5.23 | 5.22 |
| Quartile 4 | 5.15 | 5.08 |
| P for trend | 0.25 | 0.25 |
| FAI, nmol/Lc | ||
| Quartile 1 | 5.04 | 5.09 |
| Quartile 2 | 5.12 | 5.13 |
| Quartile 3 | 5.22 | 5.20 |
| Quartile 4 | 5.28 | 5.24 |
| P for trend | 0.003 | 0.04 |
| FEI, nmol/Lc | ||
| Quartile 1 | 5.07 | 5.12 |
| Quartile 2 | 5.07 | 5.09 |
| Quartile 3 | 5.21 | 5.20 |
| Quartile 4 | 5.29 | 5.22 |
| P for trend | 0.22 | 0.64 |
a
Model 1, adjusted for development of CVD and age.
b
Model 2, adjusted for development of CVD, age, and BMI.
c
Geometric means.
Abbreviations: HbA1c, glycosylated hemoglobin; HT, hormone therapy; SHBG, sex hormone-binding globulin; FAI, free androgen index; FEI, free estrogen index.