TABLE VI.
Summary of findings from breast cancer screening trials in high-risk women
| Reference | Country | Participants (n) | Rounds | Total cancers | Cancers/round (%) | Cancers/participants (%) |
Mammography |
Ultrasonography |
Magnetic resonance imaging |
|||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Snsv. (%) | Spec. (%) | Snsv. (%) | Spec. (%) | Snsv. (%) | Spec. (%) | |||||||
| Kriege et al., 200427 | Netherlands | 1909 | 1909 | 44 | 2.3 | 2.3 | 33.3 | 95 | — | — | 79.5 | 89.8 |
| Warner et al., 200429 | Canada | 236 | 457 | 22 | 4.8 | 9.3 | 36 | 99.8 | 33 | 96 | 77 | 95.4 |
| Kuhl et al., 200526 | Germany | 529 | 1542 | 43 | 2.8 | 8.1 | 33 | 96.8 | 40 | 90.5 | 91 | 97.2 |
| Leach et al., 2005 (maribs)28 | United Kingdom | 649 | 1881 | 35 | 1.9 | 5.4 | 40 | 93 | — | — | 77 | 81 |
| Lehman et al., 200732 | United States | 171 | 171 | 6 | 3.5 | 3.5 | 33 | 97.7 | 17 | 97.7 | 100 | 91.8 |
| Riedl et al., 200739 | Austria | 327 | 672 | 28 | 4.2 | 8.6 | 50 | 98 | 42.9 | 98 | 85.7 | 92 |
| Sardanelli et al., 200731 | Italy | 278 | 377 | 18 | 4.8 | 6.5 | 59 | 98.8 | 65 | 97.8 | 94 | 96.7 |
| Current study | Canada | 184 | 387 | 12 | 3.1 | 6.5 | 58 | 95.4 | 42 | 93.8 | 83 | 93.6 |
Snsv. = sensitivity; Spec. = specificity.