Patient A.

Treatment management supplemental chart notes

Patient: Joe Smith, age 38

Diagnoses: major depression and generalized anxiety disorder

Visit #: 1 Date: January 7, 2007 CGI-S = 5 Predominant symptoms: Depression and anxiety Tolerability? N/A medication to begin this evening Medication? SSRI initiated (name and dose)

Visit #: 2 Date: February 7, 2007 CGI-S=5 (markedly ill), CGI-I=4 (no change) Predominant symptoms: depression and anxiety Tolerability? slight headache one evening that resolved on own Medication? SSRI raised by 20mg

Visit#: 3 Date: March 7, 2007 CGI-S= 6 (severely ill), CGI-I=5 (minimally worse) (remember this is always in comparison to the CGI-S that was done prior to medication--thus, this is in comparison to the CGI-S of 5 at Visit 1) Predominant symptoms: Depression stayed the same; anxiety has worsened Tolerability? No problems Medication: Switch of medication to second SSRI [name, dose] due to lack of efficacy for anxiety (CGI-I has worsened despite dose increase and adequate length of time)

Visit #: 4 Date: April 7, 2007 CGI-S= 3 (mildly ill) CGI-I=3 (minimally improved) Predominant symptoms: Depression and anxiety have both improved to a minimal degree relative to baseline Tolerability? No problems Medication: SSRI #2 maintained at current dose

Visit #: 5 Date: May 7, 2007 CGI-S=2 (borderline ill) CGI-I=1 (very much improved) Predominant symptoms: Both depression and anxiety have improved dramatically Tolerability? daytime sleepiness Medication: SSRI #2 maintained at current dose; switched from am to hs dosing