Table 2.
Levels of CEL and antigen binding to mAb 103-E3 determined in all investigated cohorts.
| RA versus SLE versus HC | RA versus OA | ||||
|---|---|---|---|---|---|
| RA | SLE | HC | RA | OA | |
| Equivalents of CEL-crystallin (μg/ml) |
4.87 ± 1.989 |
2.92 ± 1.140 |
2.83 ± 1.437 |
5.413 ± 2.631 | 2.994 ± 2.023 |
| Equivalents of Rib-BSA (μg/ml) | 3.306 ± 0.755 | 2.287 ± 0.675 | 2.111 ± 0.620 | 2.993 ± 0.668 | 1.873 ± 0.692 |
RA - rheumatoid arthritis; SLE - systemic lupus erythematosus; OA - osteoarthritis; HC - healthy volunteers (controls). Results are expressed as means ± standard deviation of equivalents of CEL-crystallin or Rib-BSA. Samples with the level of measured antigen below the detection limit of the assay were not included in the calculation; these were 1 RA, 5 SLE, and 7 HC samples, respectively, assayed for CEL in the part "RA versus SLE versus HC", and 19 OA samples assayed for CEL and 1 OA sample assayed for 103-E3 antigen in the part "RA versus OA".