Table 1.
Gene families encoding glycolytic enzymes and the parent genes that are retroposed.
| Human | Mouse | |||||
|---|---|---|---|---|---|---|
| Gene Family | Gene Name | Position | Ret.seq. | Gene Name | Position | Ret.seq. |
| Hexokinase | HK1 | 10:71 | No | Hk1 | 10:62 | Yes (1) |
| HK2 | 02:75 | Yes (1) | Hk2 | 6:83 | No | |
| HK3 | 05:176 | No | Hk3 | 13:55 | No | |
| GCK | 07:44 | No | Gck | 11:6 | No | |
| HKDC1 | 10:71 | No | Hkdc1 | 10:62 | No | |
| Glucose Phosphate Isomerase | GPI1 | 19:40 | Yes (1) | Gpi1 | 7:34 | Yes (1) |
| Phosphofructokinase | PFKL | 21:45 | No | Pfkl | 10:77 | No |
| PFKM | 12:47 | No | Pfkm | 15:98 | No | |
| PFKP | 10:3 | No | Pfkp | 13:7 | No | |
| Aldolase | ALDOA | 16:30 | Yes (2) | Aldoa | 7:127 | Yes (18) |
| ALDOB | 09:103 | No | Aldob | 4:50 | No | |
| ALDOC | 17:24 | No | Aldoc | 11:78 | No | |
| Triosephosphate isomerase | TPI1 | 12:7 | Yes (4) | Tpi1 | 6:125 | Yes (15) |
| Glyceraldehyde 3-phosphate dehydrogenase | GAPDH | 12:7 | Yes (52) | Gapdh | 6:125 | Yes (188) |
| GAPDHS | 19:41 | No | Gapdhs | 7:30 | No | |
| Phosphoglycerate kinase | PGK1 | X:77 | Yes (3) | Pgk1 | X:102 | Yes (11) |
| Phosphoglycerate mutase | PGAM1 | 10:99 | Yes (21) | Pgam1 | 19:42 | Yes (12) |
| PGAM2 | 07:44 | No | Pgam2 | 11:6 | No | |
| PGAM5 | 12:132 | No | Pgam5 | 5:111 | Yes (1) | |
| Enolase | ENO1 | 01:9 | Yes (4) | Eno1 | 4:149 | Yes (27) |
| ENO2 | 12:7 | No | Eno2 | 6:125 | No | |
| ENO3 | 17:5 | No | Eno3 | 11:70 | No | |
| ENO4 | 10:119 | No | Eno4 | 19:59 | No | |
| Pyruvate kinase | PKLR | 01:154 | No | Pklr | 3:89 | No |
| PKM2 | 15:70 | Yes (6) | Pkm2 | 9:59 | Yes (17) | |
| Ensembl release 48 Dec 2007 | ||||||
The Position column indicates chromosomal location denoted as "chromosome number:position (millions)". The Ret. seq. column indicates whether retroposed sequences were identified for each parent gene. The number in parentheses next to "Yes" in this column indicates the total number of retroposed sequences that match the parent gene. We identified a total of 94 retroposed sequences matching glycolytic enzymes in the human genome and 291 in the mouse genome.