Table 3.
Summary of available experiments by cell line giving proportion of binding sites in the preferred classes
| Factor | Cell line | |||||
|---|---|---|---|---|---|---|
| GM128 | K562 | HeLa | HepG2 | NT2D1 | HCT116 | |
| GABP | 0.991 | 0.976 | ||||
| NRSF | 0.844 | 0.862 | ||||
| SRF | 0.851 | 0.794 | ||||
| JunD | 0.293 | 0.687 | ||||
| cFos | 0.603 | 0.475 | ||||
| cJun | 0.602 | |||||
| Max | 0.675 | |||||
| SREBP1 | 0.742 | |||||
| SREBP2 | 0.734 | |||||
| STAT1 | 0.638 | 0.519 | ||||
| TR4 | 0.870 | 0.871 | 0.910 | |||
| GATA1 | 0.736 | |||||
| GATA2 | 0.625 | |||||
| NF-E2 | 0.536 | |||||
| TCF7L2 | 0.483 | |||||
| Rad21 | 0.721 | |||||
| NFKB | 0.686 | |||||
| YY1 | 0.876 | |||||
| ZNF263 | 0.856 | |||||
This table summarises the ENCODE data for those transcription factors for which we found a motif from the MEME analysis and for which we had permission to use at the time of writing: it includes the JunD-GM128 result which is anomalously low. Other experimental treatments for cJun-K562 gave Ia6 = 0.637, Ig6 = 0.554, Ig30 = 0.573. For STAT1, the treatments were K562-Ia30 and HeLa-Ig30.