Table 3.
Top ten genes found differentially up- or down-regulated after LPS or PMA/ionomycin stimulation
| LPS stimulation | PMA/ionomycin stimulation | |||||
|---|---|---|---|---|---|---|
| Genes | Clusters2 | Fold change | Genes | Clusters2 | Fold change | |
| Up-regulation | SAA1 | C4 | 26.84 | IL2 | No3 | 9.96 |
| IL8 | C3 | 23.96 | HSP90AB1 | C6 | 8.49 | |
| CCL2 | C4 | 13.36 | NPM1 | C6 | 8.21 | |
| S100A9 | C3 | 13.33 | CD69 | No3 | 6.87 | |
| CXCL5 | C4 | 12.42 | TNFRSF9 | No3 | 6.62 | |
| S100A12 | No3 | 10.92 | NPM3 | C6 | 6.61 | |
| CXCL3 | No3 | 9.55 | HSPD1 | C6 | 6.51 | |
| CXCL2 | No3 | 7.96 | GAPDH | C6 | 6.20 | |
| CCL8 | No3 | 7.36 | RPS2 | C6 | 5.31 | |
| SOD2 | C6 | 5.85 | RAN | C6 | 5.31 | |
| Down-regulation | LYZ1 | C1 | -8.59 | THBS1 | C2 | -65.98 |
| FN11 | C1 | -7.57 | FOLR11 | C1 | -19.74 | |
| SLA-DRB1 | C8 | -3.23 | LYZ1 | C1 | -14.76 | |
| FOLR11 | C1 | -3.21 | FN11 | C1 | -12.26 | |
| CST31 | C8 | -2.80 | CSF1R | C8 | -8.15 | |
| SLA-DQB1 | C8 | -2.74 | TGFBI | C8 | -6.78 | |
| SLA-DOB | C8 | -2.69 | CST31 | C8 | -6.51 | |
| CST21 | C8 | -2.67 | CST21 | C8 | -5.80 | |
| SLA-DRA | C8 | -2.65 | CD163 | No3 | -5.59 | |
| SLA-DQA1 | C8 | -2.40 | CTSZ | C8 | -5.58 | |
1 Genes that are commonly down-regulated after LPS or PMA/ionomycin stimulation
2 The clusters refer to the hierarchical clustering reported in Figure 2 and Additional file 4
3 "No" means that the genes were found differentially expressed in only one stimulation condition and were not included in the hierarchical clustering.