Table 6.
List of differentially expressed genes in MHC class I and class II presentation pathways after stimulation by LPS or PMA/ionomycin
| Stimulation | Pathway | Gene symbol (Pig) | Fold Change |
|---|---|---|---|
| LPS | MHC I pathway | HSP90AB1 | 1.44 |
| HSPA5 | 1.41 | ||
| PSMB8 | 1.27 | ||
| PSME2 | 1.33 | ||
| MHC II pathway | CD74 | -2.01 | |
| CTSB | -1.38 | ||
| CTSL1 | 2.80 | ||
| CTSS | -1.61 | ||
| LGMN | -1.81 | ||
| SLA-DMA | -1.82 | ||
| SLA-DMB | -2.12 | ||
| SLA-DOB | -2.69 | ||
| SLA-DQA | -2.40 | ||
| SLA-DQB | -2.34 | ||
| SLA-DRA | -2.50 | ||
| SLA-DRB1 | -2.28 | ||
| SLA-DRB3 | -1.68 | ||
| PMA/ionomycin | MHC I pathway | CALR | 1.84 |
| CANX | 1.64 | ||
| HSP90AA1 | 2.06 | ||
| HSP90AB1 | 7.72 | ||
| HSP90B1 | 1.87 | ||
| HSPA1A | 1.52 | ||
| HSPA1B | -1.27 | ||
| HSPA1L | -1.33 | ||
| HSPA4 | 1.55 | ||
| HSPA5 | 1.84 | ||
| HSPA6 | 3.46 | ||
| HSPA8 | 4.16 | ||
| HSPA9 | 2.95 | ||
| HSPBP1 | 1.66 | ||
| IFNA5 | -1.48 | ||
| LTA | 2.18 | ||
| PDIA3 | 1.79 | ||
| PSMB5 | 2.68 | ||
| PSMB6 | 2.55 | ||
| PSMB8 | 2.10 | ||
| PSMB9 | 2.43 | ||
| PSME1 | 2.16 | ||
| PSME2 | 2.56 | ||
| SLA-3 | -1.29 | ||
| SLA-4 | -1.26 | ||
| SLA-6 | -2.01 | ||
| SLA-7 | -1.29 | ||
| SLA-11 | -1.95 | ||
| TAP1 | 1.85 | ||
| TAP2 | 1.41 | ||
| TNF-a | 2.83 | ||
| TRAP1 | 1.53 | ||
| MHC II pathway | CD74 | -2.40 | |
| CTSB | -2.24 | ||
| CTSS | -3.01 | ||
| LGMN | -3.71 | ||
| SLA-DMA | -2.06 | ||
| SLA-DMB | -2.31 | ||
| SLA-DOA | -1.38 | ||
| SLA-DOB | -2.50 | ||
| SLA-DQA | -3.14 | ||
| SLA-DQB | -2.62 | ||
| SLA-DRA | -2.83 | ||
| SLA-DRB1 | -3.12 | ||
| SLA-DRB3 | -2.05 | ||
| SLA-DRB5 | -1.35 | ||