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Inhibition by PQQ of the amyloid fibril formation of C-terminal-truncated α-synuclein mixed with full-length α-synuclein. 70 μM full-length α-Syn or a mixture of 35 μM full-length α-Syn and 35 μM truncated variants was incubated in PBS buffer, pH 7.4 with stirring at 37°C in the absence (white bar or gray bar) and in the presence of 280 μM PQQ (black bar). Fibril formation was measured by TfT fluorescence.
