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. 2010 May 18;10:46. doi: 10.1186/1471-230X-10-46

Table 2.

The sensitivity/specificity of each tumor marker for HCC was depicted.

Sensitivity Specificity OR PPV/NPV Cut-off point
hTERTmRNA 90.2 85.4 19.0 83.0/85.9 3. 97 (logarithmic copy number)

AFP 76.6 66.2 11.1 74.6/67.7 <10 (ng/ml)

AFP-L3 60.5 88.7 2.2 59.6/92.2 <10 (%)

DCP 83.4 80.3 7.6 78.4/73.5 <40 (mAU/ml)

The sensitivity/specificity values are 90.2%/85.4% for hTERTmRNA, 76.6%/66.2% for AFP, 60.5%/88.7% for AFP-L3, and 83.4%/80.3% for DCP. Regarding a diagnostic assessment in sensitivity and specificity, hTERTmRNA is identified as the most excellent tumor marker. OR: odds ratio, PPV: positive predictive value (%), NPV: negative predictive value (%).