Table 2.
Sensitivity | Specificity | OR | PPV/NPV | Cut-off point | |
---|---|---|---|---|---|
hTERTmRNA | 90.2 | 85.4 | 19.0 | 83.0/85.9 | 3. 97 (logarithmic copy number) |
AFP | 76.6 | 66.2 | 11.1 | 74.6/67.7 | <10 (ng/ml) |
AFP-L3 | 60.5 | 88.7 | 2.2 | 59.6/92.2 | <10 (%) |
DCP | 83.4 | 80.3 | 7.6 | 78.4/73.5 | <40 (mAU/ml) |
The sensitivity/specificity values are 90.2%/85.4% for hTERTmRNA, 76.6%/66.2% for AFP, 60.5%/88.7% for AFP-L3, and 83.4%/80.3% for DCP. Regarding a diagnostic assessment in sensitivity and specificity, hTERTmRNA is identified as the most excellent tumor marker. OR: odds ratio, PPV: positive predictive value (%), NPV: negative predictive value (%).