Table 2.
Genes coding for cell cycle regulatory molecules displaying altered expression in LP-1 derivatives (|FC|>3)
| Gene | Protein | LP-1D1b vs. cl1 | LP-1K vs. cl1 |
|---|---|---|---|
| SESN2 | Sestrin 2 | +3.36* | nm** |
| DDIT3 | DNA-damage-inducible transcript 3 | +3.35 | nm |
| CCNB1IP1 | Cyclin B1 interacting protein 1 | nm | +10.36 |
| RASSF5 | Ras association (RalGDS/AP-6) domain family member 5 | nm | +4.79 |
| CDNK1A | Cyclin-dependent kinase inhibitor 1A | nm | +4.30 |
| CABLES1 | CDK5 and ABL enzyme substract 1 | nm | +3.30 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 | nm | -3.13 |
| CCNB2 | Cyclin B2 | nm | -3.14 |
| GAS2 | Growth-arrest specific 2 | nm | -3.22 |
| MK167 | Antigen identified by monoclonal antibody Ki67 | nm | -3.37 |
| PINX1 | PIN2-interacting protein 1 | nm | -3.57 |
| CCNF | Cyclin F | nm | -3.65 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | nm | -3.68 |
| CHMP1A | Chromatin modifying protein 1A | nm | -3.87 |
| CDK6 | Cyclin-dependent kinase 6 | nm | -4.14 |
| CCNB1 | Cyclin B1 | nm | -5.23 |
| CDKN3 | Cyclin-dependent kinase inhibitor 3 | nm | -6.53 |
| CDKN2C | Cyclin-dependent kinase inhibitor 2C (p18) | nm | -8.18 |
| CDKN2B | Cyclin-dependent kinase inhibitor 2B (p15) | -3.75 | -2.83 |
* Numbers are the fold change of the sample compared to LP-1cl1; ** nm, not modified.