Table 3.
Genes coding for signalization molecules displaying altered expression in LP-1 derivatives (|FC|>3)
| Gene | Protein | LP-1D1b vs. cl1 | LP-1K vs. cl1 |
|---|---|---|---|
| FGFR3 | Fibroblast growth factor receptor 3 | +5.08* | nm** |
| AKT3 | v-akt oncogene homolog 3 | nm | -5.16 |
| MET | HGFR, Met proto-oncogene | nm | -4.33 |
| ITPKA | Inositol 1,4,5-triphosphate 3-kinase A | nm | -3.94 |
| CD81 | CD81 molecule | nm | +3.03 |
| PIK3CG | Phosphoinositide 3-kinase gamma | nm | +3.20 |
| DOK6 | Docking protein 6 | nm | +3.21 |
| MAPK13 | MAP kinase 13 | nm | +3.25 |
| ECOP | EGFR-overexpressed protein | nm | +3.39 |
| PRKD2 | Protein kinase D2 | nm | +3.94 |
| DUSP6 | Dual specificity phosphatase 6 | nm | +8.37 |
| SKAP1 | Src kinase associated phosphoprotein | nm | +9.28 |
| SYK | Spleen tyrosine kinase | nm | +9.87 |
| MAPK12 | MAP kinase 12 | nm | +10.10 |
| BLK | B lymphoid tyrosine kinase | +2.39 | +12.25 |
*, ** see legend of Table 2.