TABLE 3.
The nature and location of mutations found in this study
| Gene | Sequenced mutant line | Nucleotide changes | Amino acid changes | Location of mutation |
|---|---|---|---|---|
| CG41265 (l(2)41Ab) | EMS45-10 | G → A | (W → stop) | +93785 (exon 7) |
| CG42595 (uex) | L2 | C → T | Q → STOP | +10139 (exon 4) |
| NC1 | 13-bp deletion and 4-bp deletion | frameshift + possible loss of a splice junction motif | +9949 to +9961 (exon 11) and +9989 to +9991 (intron 11) | |
| uex34-7 | G → C | M → I | +3 (putative transcription start site) | |
| CG17683 | NC109 | T → A and T → G | V → D and S → A | +559 and +564 (exon 3) |
| NC38 | T → A | C → STOP | +602 (exon 3) | |
| EMS 34-13 | C → T | S → F | +658 (exon 3) | |
| CG40127 | NC110 | T → A | L → H | +375 (exon 3) |
| CG17665 | EMS 45-34 | G → A | W → STOP | +3917 (exon 3) |
| EMS 45-61 | C → T | R → STOP | +6088 (exon 7) | |
| EMS 45-71 | G → A | G → E | +4168 (exon 3) | |
| NC19 | G → A | W → STOP | +3736 (exon 3) | |
| NC28 | T → A | L → P | +3796 (exon 3) |
Genes are listed in the proximal to distal direction. The location of the mutation is written as the number of amino acids downstream (+) or upstream (−) from the predicted translation start site (+0).