TABLE 7.
A summary of the essential loci in this study, listed from proximal to distal
| Essential locus uncovered | Methods used to uncover locus | Homologs |
|---|---|---|
| CG41265 (l(2)41Ab) | Sequencing 1 allele | Similar to myosin heavy polypeptide 9, nonmuscle, (rat), 2e-47 |
| Ccdc40 mouse 2e-17 | ||
| Myosin heavy chain A (Schmidtea mediterranea), 3e-15 | ||
| Centromere protein E (CENP-E) (human), 9e-10 | ||
| CG17684 | RNAi | DPPY (DPP10, dipeptidyl peptidase) (human), 6e-74 |
| uex (CG42595) | Genetic analysis and sequencing three alleles | Cyclin M2, 3E-168 |
| CG17683 | Genetic analysis, RNAi, and sequencing three alleles | Nuclear prelamin A recognition factor-like (rat), 8.00E-147 |
| CG40127 | Genetic analysis and sequencing 1 allele | Salivary secreted ribonucleaes (Culex pipiens quinquefasciatus), 1e-27 |
| RnaseK (mouse), 3e-10 | ||
| CG17665 | Genetic analysis, RNAi and sequencing five alleles | Integrator complex subunit 3 (mouse), E = 0 |
| CG17883 | RNAi | TBC1 domain family member 20 (human), 4.00E-65 |
| Atf6 | RNAi | ATF6 (human), 2e-16 |
Six novel essential loci were uncovered while the molecular identity of two previously reported essential loci, l(2)41Ab and uex, was discovered. Putative homologs were determined using BLASTp available at http://blast.ncbi.nlm.nih.gov.