. 2010 Jun;185(2):603–609. doi: 10.1534/genetics.110.115162

TABLE 2.

Mutational fitness effects (s) of missense mutations for different functional categories

	Genes	Mean^a	Variance^a	Number^a	Lethal fraction
Replication	II, X	0.535	0.214	15	47%
Maturation	I, V	0.362	0.205	8	25%
Capsid	III, VI, VII, VIII, IX	0.305	0.130	13	15%
Extrusion	IV	0.270	0.113	15	7%
Total		0.371	0.164	51	24%

For all mutations (including lethals).