TABLE 2.
True QTL location in centimorgans (cM) as well as posterior means and standard deviations of δ, μ, a, and σe2 obtained by the exact and two-step approaches for selected replicates of the simulation with 1500 effective individuals in the base population and a heritability of 0.05
| Method | Replicate | True δ, cM |
, cM |
a
|
b
|
c
|
|---|---|---|---|---|---|---|
| Exact | 1 | 0.60 | 0.62 (±0.05) | 0.00 (±0.09) | 0.43 (±0.10) | 0.91 (±0.07) |
| 2 | 0.42 | 0.44 (±0.24) | 0.03 (±0.10) | 0.21 (±0.12) | 1.02 (±0.09) | |
| 3 | 0.25 | 0.35 (±0.09) | −0.08 (±0.11) | 0.37 (±0.12) | 0.94 (±0.08) | |
| 4 | 0.59 | 0.54 (±0.26) | 0.00 (±0.11) | 0.20 (±0.12) | 1.03 (±0.09) | |
| 5 | 0.38 | 0.39 (±0.22) | 0.03 (±0.12) | 0.28 (±0.15) | 1.04 (±0.09) | |
| 6 | 0.52 | 0.48 (±0.17) | 0.06 (±0.13) | 0.29 (±0.15) | 1.08 (±0.09) | |
| Two-step | 1 | 0.60 | 0.66 (±0.04) | −0.02 (±0.10) | 0.42 (±0.12) | 0.91 (±0.07) |
| 2 | 0.42 | 0.51 (±0.29) | 0.03 (±0.10) | 0.20 (±0.11) | 1.01 (±0.08) | |
| 3 | 0.25 | 0.35 (±0.07) | −0.07 (±0.11) | 0.37 (±0.15) | 0.93 (±0.08) | |
| 4 | 0.59 | 0.56 (±0.23) | 0.00 (±0.10) | 0.21 (±0.12) | 1.02 (±0.09) | |
| 5 | 0.38 | 0.52 (±0.19) | 0.02 (±0.10) | 0.24 (±0.14) | 1.03 (±0.09) | |
| 6 | 0.52 | 0.43 (±0.23) | 0.04 (±0.11) | 0.23 (±0.13) | 1.07 (±0.09) |
μ = 0.
a = 0.324.
.



