Table 4.

The Val Allele Homozygotes of ABCG2 Val12Met, Compared With the Met Allele Carriers Are Associated With Increased Risk of Incident Ischemic Stroke in Both White and Black Participants of CHS

	ABCG2 Genotype	Events, n	Total, n	Model 1*		Model 2*
				HR (90% CI)	P	HR (90% CI)	P
White	ValVal	370	3398	1.58 (1.12–2.23)	0.02	1.50 (1.06–2.12)	0.03
	ValMet+MetMet	24	335	1 (Reference)		1 (Reference)
	ValMet	23	321
	MetMet	1	14
Black	ValVal	66	592	3.80 (1.16–12.4)	0.03	3.62 (1.11–11.9)	0.04
	ValMet+MetMet	2	70	1 (Reference)		1 (Reference)
	ValMet	2	69
	MetMet	0	1

^*Model 1 was adjusted for baseline age and sex. Model 2 was adjusted for baseline age, sex, body mass index, current smoking, diabetes, impaired fasting glucose, hypertension, LDL cholesterol, and HDL cholesterol.