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Sost expression is unaltered by VEGF signaling. Manipulation of VEGF signaling with recombinant VEGF165 or VEGF-inhibiting antibody revealed no effect upon Sost expression, regardless of oxygen tension. Bars represent mean Sost transcript ±SEM normalized to 21% oxygen. n = 4 per condition. *P<0.05 compared to 21% oxygen.
