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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Neurobiol Learn Mem. 2010 Apr 11;94(1):57–64. doi: 10.1016/j.nlm.2010.04.001

Figure 2. Older rats infected as neonates exhibit a cognitive impairment in the ambiguous cue task.

Figure 2

Rats were treated on P4 with PBS or E. coli, and tested for memory at 2 month or 16 month of age using a task that requires the animal to distinguish between multiple cues that predict a shock with varying fidelity. Figures represent percent freezing to each cue minus baseline (“no cue”) freezing at 48 hr (A) or 1 wk (B) after conditioning. *freezing to the light is significantly different overall from freezing to the tone; **freezing is overall higher in 16 month compared to 2 month old rats; #significantly different from PBS/Tone group; p<0.05 for all.