Figure 5. Glial markers and NMDA receptor subunit composition are altered with age.
Rats treated on P4 with PBS or E. coli were sacrificed at 2 or 16 month of age, following the completion of behavioral testing. All statistics were performed on raw data, but data are presented here as relative changes in gene expression in the 16 month olds compared to 2 month olds in order to better illustrate age-associated changes. #significantly different overall from 2 month olds, *significantly different overall from PBS, **significantly different from PBS within the dentate gyrus (DG), p<0.05 for all. CD11b=complement 3 receptor, a marker for microglia; MHC II=major histocompatibility complex, a marker for microglia; GFAP=glial fibrillary acidic protein, a marker for astrocytes; AMY=Amygdala; PAR=parietal cortex.
