Figure 7. CRCL overcomes TGF-β-mediated DC suppression.
Day 5 bone marrow derived DC were incubated for 24 hrs with CRCL (25 μg/ml) or LPS (1 μg/ml), with or without TGF-β (10 ng/ml). The supernatants were harvested after 24 hrs and tested for TNF-α production by ELISA. *, a significant difference when compared to DC treated with LPS without TGF-β (p<0.05). NS, non-significant difference when compated to DC treated with CRCL without TGF-β.
