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. Author manuscript; available in PMC: 2011 Jul 25.
Published in final edited form as: Eur J Pharmacol. 2010 Apr 28;638(1-3):61–64. doi: 10.1016/j.ejphar.2010.04.020

Fig. 2. Sensitivity of topical mu opioid analgesia to naloxone.

Fig. 2

Groups (n=10) of animals received systemic naloxone (1 mg/kg, s.c.) given in the midscapular region 20 min or saline before topical drug administration of the indicated opiate (10 mM). Analgesia was assessed using the tail-flick assay, as described under Methods.