Table 2.

Blood metabolites and intracellular phenylalanine

		Baseline	Exercise	1 hr Post	2 hr Post
Male	Blood flow (ml • min−1 • 100mg of leg LM−1)	4.40 ± 0.1	17.17 ± 2.1*	5.90 ± 0.8	4.82 ± 0.5
	Glucose concentration (mg • dl−1)
	Femoral artery	94 ± 2	107 ± 5*b	96 ± 3	92 ± 3
	Femoral vein	93 ± 2	104 ± 5*b	94 ± 3	88 ± 3
	Lactate (mmol • L−1)
	Femoral artery	0.75 ± 0.1	9.95 ± 0.9*b	2.12 ± 0.3	0.86 ± 0.1
	Femoral vein	0.80 ± 0.1	12.10 ± 0.9*†	2.31 ± 0.2*	1.00 ± 0.1
	Blood pH
	Femoral artery	7.41 ± 0.01	7.31 ± 0.01*	7.40 ± 0.01	7.41 ± 0.01
	Femoral vein	7.37 ± 0.01	7.17 ± 0.01*b	7.36 ± 0.01	7.37 ± 0.01
	Phenylalanine concentration (μmol • L−1)
	Femoral artery	54 ± 2	56 ± 2	54 ± 2	54 ± 1
	Femoral vein	58 ± 2	57 ± 2	58 ± 2	57 ± 2
	Muscle intracellular	78 ± 5	86 ± 6*	76 ± 5	64 ± 3
Female	Blood flow (ml • min−1 • 100mg of leg LM−1)	5.10 ± 0.8	18.34 ± 3.5*	7.50 ± 1.0	6.81 ± 1.0
	Glucose concentration (mg • dl−1)
	Femoral artery	88 ± 2	98 ± 3*	89 ± 2	87 ± 2
	Femoral vein	86 ± 2	95 ± 3*	86 ± 3	83 ± 3
	Lactate (mmol • L−1)
	Femoral artery	0.64 ± 0.1	8.21 ± 0.5*	1.94 ± 0.2	0.7 ± 0.1
	Femoral vein	0.68 ± 0.1	9.68 ± 0.6*	2.21 ± 0.2a	0.89 ± 0.1
	Blood pH
	Femoral artery	7.41 ± 0.01	7.32 ± 0.01*	7.39 ± 0.01	7.40 ± 0.01
	Femoral vein	7.37 ± 0.01	7.20 ± 0.01*	7.36 ± 0.01	7.36 ± 0.01
	Phenylalanine concentration (μmol • L−1)
	Femoral artery	54 ± 4	56 ± 4	54 ± 4	53 ± 4
	Femoral vein	59 ± 4	58 ± 5	58 ± 6	57 ± 4
	Muscle intracellular	73 ± 3	85 ± 3*	68 ± 2	63 ± 4

^*P<0.05 vs. Baseline;

^†P<0.05 vs. Female;

^aP<0.1 vs. Baseline;

^bP<0.1 vs. Female.