Table 1.
The nectin/nectin-like family of genes.
| Member | Alternative nomenclature | Proposed functions | References |
|---|---|---|---|
| Nectin-1 | PRR1, HVEC | Cell-cell adhesion molecule | [23] |
| α-HSV receptor | [22] | ||
| Involved in dysraphism (cleft lip/palate-ectodermal dysplasia syndrome) (cleft lip/palate-ectodermal dysplasia syndrome) | [24] | ||
| Nectin-2 | PRR2, HVEB | Cell-cell adhesion molecule | [25] |
| α-HSV receptor | [22] | ||
| Nectin-3 | PRR3 | Cell-cell adhesion molecule | [26] |
| Nectin-4 | Cell-cell adhesion molecule | [27] | |
| Necl-1 | TSLL1, SynCAM3 | Cell-cell adhesion molecule in the CNS | [28,29] |
| Necl-2 | IGSF4, RA175, SgIGSF, TSLC1, SynCAM1 | Cell-cell adhesion molecule | [29] |
| Necl-3 | SynCAM2 | Putative cell-cell adhesion molecule | [30] |
| Necl-4 | TSLL2, SynCAM4 | Cell-cell adhesion molecule in the CNS | [31] |
| Necl-5 | Tage4, PVR, CD155 | Poliovirus receptor | [20] |
| Associated with malignancy | [32-36] |