Table 3.
Poisson regressions for shedding and lesions.
| genital shedding | oral shedding | |||
|---|---|---|---|---|
| RR (95% C.I.a) | P | RR (95% C.I.a) | P | |
| any APOE4 versus none | 0.94 (0.68–1.29) | 0.69 | 1.65 (0.69–3.97) | 0.26 |
| any APOE4 versus noneb | 0.93 (0.68–1.29) | 0.68 | 1.61 (0.68–3.79) | 0.28 |
| male gender | 0.87 (0.64–1.18) | 0.37 | 1.41 (0.58–3.46) | 0.45 |
| HSV-1 and HSV-2 infection | 1.23 (0.91–1.67) | 0.17 | 3.35 (0.52–21.77) | 0.21 |
| genital lesions | oral lesions | |||
| RR (95% C.I.a) | P | RR (95% C.I.a) | P | |
| any APOE4 versus none | 0.93 (0.61–1.41) | 0.72 | 4.64 (1.32–15.05) | 0.016 |
| any APOE4 versus noneb | 0.86 (0.57–1.29) | 0.45 | 4.04 (1.09–15.01) | 0.037 |
| male gender | 1.02 (0.69–1.52) | 0.91 | 1.57 (0.37–6.59) | 0.54 |
| HSV-1 and HSV-2 infection | 1.08 (0.73–1.60) | 0.70 | 0.74 (0.16–3.39) | 0.70 |
| history of genital herpes | 5.13 (2.20–11.98) | <0.001 | -- | -- |
C.I. stands for confidence interval.
Risk ratio adjusted for gender, co-infection, time since infection, and symptoms at site. Data set on oral symptoms is incomplete so no adjustment is made for oral shedding.